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2022

HTG Therapeutics White Paper HTP Proof of Concept

A Proof-of-concept Exploration of Transcriptome-informed
Drug Discovery Using the HTG Transcriptome Panel

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T-cell prolymphocytic leukemia is associated with deregulation of oncogenic microRNAs on transcriptional and epigenetic level

Paurnima, P., et al., T-cell prolymphocytic leukemia is associated with deregulation of oncogenic microRNAs on transcriptional and epigenetic level

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Atezolizumab with enzalutamide versus enzalutamide alone in metastatic castration-resistant prostate cancer: a randomized phase 3 trial

Powles, T., et al., Atezolizumab with enzalutamide versus enzalutamide alone in metastatic castration-resistant prostate cancer: a randomized phase 3 trial

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Placental genomics mediates genetic associations with complex health traits and disease

Bhattacharya, A., et al., Placental genomics mediates genetic associations with complex health traits and disease

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Cellular miR-150-5p may have a crucial role to play in the biology of SARS-CoV-2 infection by regulating nsp10 gene

Akula, S., et al., Cellular miR-150-5p may have a crucial role to play in the biology of SARS-CoV-2 infection by regulating nsp10 gene

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Abstract PD2-07: Impact of using cross-platform gene expression profiling technologies and computational methods for intrinsic breast cancer subtyping in PALOMA-2 and PALLET

Cheang, M. et al., Abstract PD2-07: Impact of using cross-platform gene expression profiling technologies and computational methods for intrinsic breast cancer subtyping in PALOMA-2 and PALLET

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Oropharyngeal cancer outcomes correlate with p16 status, multinucleation and immune infiltration

Authors used the HTG EdgeSeq Oncology Biomarker Panel  and machine learning tools (AI) to identify biomarkers which can be used to develop precision oncology diagnostic tools for oropharyngeal squamous cell carcinoma patients. OPSCC is caused mostly by the HPV virus.

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Page last updated May 22, 2023