HTG EdgeSeq Immune Response Panel
Measure 2,002 immune response mRNA targets in a single RNA extraction-free panel. The HTG EdgeSeq Immune Response Panel leverages the sensitivity and dynamic range of next-generation sequencing (NGS) to measure genes implicated in the immune response including response to pathogens and a variety of autoimmune diseases. The HTG EdgeSeq Immune Response Panel enables multiplex profiling from FFPE and PAXgene samples.
For Research Use Only. Not for Use in Diagnostic Procedures.
2020 HTG EdgeSeq Immune Response Panel Research Grants.
University of Pennsylvania
Department of Pathology and Laboratory Medicine
Features and Benefits
- Measure 2,002 transcripts in a single well: obtain a broad profile of genes associated with immune response to pathogen infection and autoimmune disease.
- Extraction-free chemistry: the simple workflow reduces extraction-associated data bias and sample loss
- Low sample input: reliable, reproducible performance from FFPE and PAXgene samples
- Simplified data analysis: analyze results in the HTG EdgeSeq Reveal data suite, not a complicated RNA-Seq pipeline
Or, explore the all new HTG EdgeSeq Immune Response Panel Explorer Tool.
Sample Requirements
| Sample Type | Recommended Sample Input |
|---|---|
Larger sample input amounts must be diluted. Please consult the assay package insert and HTG EdgeSeq System User Manual for more details. |
|
| FFPE Tissue | One 5 µm section |
| PAXgene | 500 µl |
A Sampling of Autoimmune Diseases Targeted by the HTG EdgeSeq Immune Response Panel
| Rheumatoid arthritis | Psoriasis | Multiple sclerosis |
| Irritable bowel disease | Lupus | Diabetes mellitus |
| Crohn's disease | Autoimmune arthritis | Immunosuppression |
Discover more about the HTG EdgeSeq Immune Response Panel by clicking here!
Ordering Information
When placing an order, please specify the catalog number. The HTG EdgeSeq Immune Response Panel is compatible with Illumina sequencers.
Kit Configurations for use with the Illumina Sequencers
916-015-208 HTG EdgeSeq Immune Response Panel (2X8)
916-015-008 HTG EdgeSeq Immune Response Panel (4X8)
916-015-224 HTG EdgeSeq Immune Response Panel (1X24)
916-015-024 HTG EdgeSeq Immune Response Panel (4x24)
916-015-096 HTG EdgeSeq Immune Response Panel (1x96)
Kit Configurations for use with the Thermo Fisher Scientific Ion Torrent Sequencers
916-015-308 HTG EdgeSeq Immune Response Panel (2x8)
916-015-108 HTG EdgeSeq Immune Response Panel (4x8)
916-015-324 HTG EdgeSeq Immune Response Panel (1x24)
916-015-124 HTG EdgeSeq Immune Response Panel (4x24)
916-015-196 HTG EdgeSeq Immune Response Panel (1x96)
For Research Use Only. Not for Use in Diagnostic Procedures.
Resources and Publications
Learn more about the HTG EdgeSeq Immune Response Panel
HTG EdgeSeq Immune Response Panel Gene List
Download pdf 215KB
HTG EdgeSeq Immune Response Panel COVID-19 SARS-CoV-2 Case Study
Download pdf 683KB
HTG EdgeSeq Immune Response Panel Product Sheet
Download pdf 1.1MB
HTG EdgeSeq Immune Response Panel Annotated Gene List
Download pdf 276KB
Publications
Transcriptomic signatures in melanoma lymph node metastasis that relate to immune oncology treatment
View External Link
COVID-19 patients are characterized by dysregulated levels of membrane and soluble CD48
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Immunohistochemical and Transcriptional Analysis of SARS-CoV-2 Entry Factors and Renin-Angiotensin-Aldosterone System Components in Lethal COVID-19
Download pdf 1.3MB
View External Link
Vascular Damage, Thromboinflammation, Plasmablast Activation, T-Cell Dysregulation and Pathological Histiocytic Response in Pulmonary Draining Lymph Nodes of COVID-19
Download pdf 11.1MB
View External Link
Deleterious Genetic Variation Across the NOD Signaling Pathway Is Associated With Reduced NFKB Signaling Transcription and Upregulation of Alternative Inflammatory Transcripts in Pediatric Inflammatory Bowel Disease
Download pdf 7.7MB
View External Link
Transcriptome and unique cytokine microenvironment of Castleman disease
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IgA autoantibodies target pulmonary surfactant in patients with severe COVID-19
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Ileal transcriptomic analysis in pediatric Crohn's disease reveals IL17-and NOD-signaling expression signatures in treatment-naïve patients and identifies epithelial cells driving differentially expressed genes
Download pdf 6.4MB
Learn More
For further information about the HTG EdgeSeq Immune Response Panel please fill out the registration form below or call us at (877) 507-3259.
Page last updated June 29, 2022