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2018

PQR309 is a novel dual P13K/mTOR inhibitor with pre-clinical anti-tumor activity in lymphomas as a single agent and in combination therapy.

Bertoni, F., et al. PQ309 is a novel dual P13K/mTOR inhibitor with pre-clinical anti-tumor activity in lymphomas as a single agent and in combination therapy. Clin Cancer Res. Clin Cancer Res. 2018 Jan 1;24(1):120-129. doi: 10.1158/1078-0432.CCR-17-1041. Epub 2017 Oct 24. [Epub ahead of print].

PMID: 29066507

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2017

Heterogeneity in immune biomarker expression after acquisition of resistance to EGFR kirase inhibitors: Analysis of a case with small cell lung cancer transformation

Suda et. al. Heterogeneity in immune biomarker expression after acquisition of resistance to EGFR kirase inhibitors: Analysis of a case with small cell lung cancer transformation; J Thorac Oncol. 2017 Jun; 1216: 1015 

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The immune microenvironment of HPV-negative oral squamous cell carcinoma from never-smokers and never-drinkers patients suggests higher clinical benefit of IDO1 and PD1/PD-L1 blockade

Foy JP., et al. The immune microenvironment of HPV-negative oral squamous cell carcinoma from never-smokers and never-drinkers patients suggests higher clinical benefit of IDO1 and PD1/PD-L1 blockade. Ann Oncol. 2017 Aug 1; 28(8):1934

PMID: 28460011

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